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Anti-apoptotic and Pro-inflammatory Signaling in Cancer Cells. Status and Modulation by Chemotherapeutic Drugs

Код 901397

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Аннотация к книге "Anti-apoptotic and Pro-inflammatory Signaling in Cancer Cells. Status and Modulation by Chemotherapeutic Drugs"

The transcription factor nuclear factor kappa-B (NFkB) plays a pivotal role in the immune response but is also involved in cancer development and progression. In unstimulated cells NFkB is kept inactive in the cytoplasm by inhibitor of NFkB (IkB) proteins. Dysregulation of the pathway or activation of NFkB by chemotherapeutic agents may lead to cancer progression or drug resistance. The NFkB activation status was investigated in human lung cancer, pancreatic cancer, and hematopoietic cancer...

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Издательство: Книга по требованию
Дата выхода: июль 2011
ISBN: 978-3-6390-0750-3
Объём: 128 страниц
Масса: 215 г
Размеры(высота, ширина, толщина), см: 23 x 16 x 1

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