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AAV-mediated gene therapy for renal tubulointerstitial fibrosis. HGF as a multifunctional anti-fibrotic agent with high impact on gene therapy for renal tubulointerstitial fibrosis

Код 1454134

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Аннотация к книге "AAV-mediated gene therapy for renal tubulointerstitial fibrosis. HGF as a multifunctional anti-fibrotic agent with high impact on gene therapy for renal tubulointerstitial fibrosis"

Fibrotic processes in chronic kidney diseases are the leading cause of renal failure. Hepatocyte growth factor (HGF), effecting organ restructuring by its mitogenic, motogenic, morphogenic and anti-apoptotic activities, is one of the central mediators involved in tubular repair and regeneration after acute renal injury. In addition, HGF acts as an anti-inflammatory and anti-fibrotic factor antagonizing pro-fibrotic actions of transforming growth factor (TGF ). However, the molecular and...

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Издательство: Книга по требованию
Дата выхода: июль 2011
ISBN: 978-3-8381-1991-5
Объём: 132 страниц
Масса: 221 г
Размеры(высота, ширина, толщина), см: 23 x 16 x 1

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