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Assay Development for Lysyl Hydroxylase. A new HPLC method for efficient separation of lysine- from hydroxylysine-containing peptides

Код 914608

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Аннотация к книге "Assay Development for Lysyl Hydroxylase. A new HPLC method for efficient separation of lysine- from hydroxylysine-containing peptides"

Hydroxylysine is produced as a posttranslational modification mainly in collagens, the most abundant protein in mammals. Lysyl hydroxylase (LH) is the enzyme that catalyzes the formation of hydroxylysyl residues in collagen by hydroxylation of -X-Lys-Gly- sequences. In order to study the hydroxylation reaction catalysed by LH, we have synthesized 4 different peptides and the corresponding hydroxylated peptide using Fmoc solid-phase methodology. Peptides have been characterized by HPLC, mass...

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Издательство: Книга по требованию
Дата выхода: июль 2011
ISBN: 978-3-6392-2257-9
Объём: 68 страниц
Масса: 123 г
Размеры(высота, ширина, толщина), см: 23 x 16 x 1

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