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Computational Prediction of Aggregated Structure of Denatured Lysozyme. Rosetta++ software creating in silico models and docking them into aggregates. Here we found two amazing results

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Аннотация к книге "Computational Prediction of Aggregated Structure of Denatured Lysozyme. Rosetta++ software creating in silico models and docking them into aggregates. Here we found two amazing results"

Mis-folded proteins and their associated aggregates are a contributing factor in some human diseases. In this study we used the protein lysozyme as a model to define aggregation structures under denaturing conditions. We used Rosetta++ protein folding and blind docking software to create in silico models of the protein at denaturing temperatures and subsequently docked them into aggregates. Here we compare those structures and select forms consistent with the fibril structure from the previous...

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Издательство: Книга по требованию
Дата выхода: июль 2011
ISBN: 978-3-8433-7625-9
Объём: 88 страниц
Масса: 153 г
Размеры(высота, ширина, толщина), см: 23 x 16 x 1

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