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Cytotoxic Mechanisms of Iron Chelators with Therapeutic Potential. Identification of cytotoxic mechanisms of iron chelators with potential for the treatment of cancer and iron overload

Код 1236166

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Аннотация к книге "Cytotoxic Mechanisms of Iron Chelators with Therapeutic Potential. Identification of cytotoxic mechanisms of iron chelators with potential for the treatment of cancer and iron overload"

For many years iron chelators have been used for the treatment of iron overload disease and cancer. Nonetheless, the development of novel synthetic chelators with improved bioavaliability and reduced cytotoxicity remains an area of much interest. This thesis is an examination of some mechanisms through which iron binding agents cause toxicity. Two novel classes of iron chelator were compared to clinically relevant chelators with a range of cytotoxic profiles. A variety of assays were employed...

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Издательство: Книга по требованию
Дата выхода: июль 2011
ISBN: 978-3-6391-4780-3
Объём: 172 страниц
Масса: 282 г
Размеры(высота, ширина, толщина), см: 23 x 16 x 1

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