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Development of Tolerance and Dependence in Barbiturate Use

Код 1230000

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Аннотация к книге "Development of Tolerance and Dependence in Barbiturate Use"

A mathematical model is constructed to study the development of tolerance and dependence to phenobarbital in continuous use. Phenobarbital is a sedative drug targeting the brain. As a side effect, it enhances its own metabolism rate. Also in regular use, the brain adapts to its presence and is rendered less sensitive to the drug with time. This decrease in drug effectiveness urges the user to increase the dose. A feedback loop results as the increased dose affects metabolism and neuroadaptation...

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Издательство: Книга по требованию
Дата выхода: июль 2011
ISBN: 978-3-8383-0558-5
Объём: 108 страниц
Масса: 184 г
Размеры(высота, ширина, толщина), см: 23 x 16 x 1

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