книги Наука, техника, медицина Гуманитарные науки Общественные науки Социология Общая и теоретическая социология Анализ данных и исследования

Erythropoietin receptor

Код 3424942

  • ISBN: 978-5-5088-7432-2

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Аннотация к книге "Erythropoietin receptor"

High Quality Content by WIKIPEDIA articles! The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. EpoR is a 59 kDa peptide and is a member of the cytokine receptor family. EpoR pre-exists as dimers which upon binding of a 34 kDa ligand erythropoietin (Epo), changes its homodimerized state. These conformational changes result in the autophosphorylation of Jak2 kinases that are pre-associated with the receptor (i.e., EpoR does not possess intrinsic kinase activity and depends on Jak2 activity). At present, the most well-established function of EpoR is to rescue erythroid (red blood cell) progenitors from apoptosis.

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ISBN: 978-5-5088-7432-2

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Биология Путешествия, туризм, природа Домашние животные

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