Gamma secretase
Код 3194144
- ISBN: 978-5-5139-1512-6
Код 3194144
High Quality Content by WIKIPEDIA articles! Gamma secretase is a multi-subunit protease complex, itself an integral membrane protein, that cleaves single-pass transmembrane proteins at residues within the transmembrane domain. Proteases of this type are known as intramembrane proteases. The most well-known substrate of gamma secretase is amyloid precursor protein, a large integral membrane protein that, when cleaved by both gamma and beta secretase, produces a short 17-42amino acid peptide...
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