Аннотация к книге "Transforming Growth Factor Beta Superfamily"
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The transforming growth factor beta (TGF- ) superfamily is a large family of structurally related cell regulatory proteins that was named after its first member, TGF- 1, originally described in 1983.Transforming growth factor-beta (TGF-beta) is a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. TGF-beta-1 is a...
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The transforming growth factor beta (TGF- ) superfamily is a large family of structurally related cell regulatory proteins that was named after its first member, TGF- 1, originally described in 1983.Transforming growth factor-beta (TGF-beta) is a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. TGF-beta-1 is a peptide of 112 amino acid residues derived by proteolytic cleavage from the C-terminal of a precursor protein. These proteins interact with a conserved family of cell surface serine/threonine-specific protein kinase receptors, and generate intracellular signals using a conserved family of proteins called SMADs. They play fundamental roles in the regulation of basic biological processes such as growth, development, tissue homeostasis and regulation of the immune system.
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