14-Phenylpropoxymetopon
Frederic P. Miller, Agnes F. Vandome, John McBrewster
High Quality Content by WIKIPEDIA articles! 14-Phenylpropoxymetopon (PPOM) is an opiate analogue that is an derivative of metopon which has been substituted with a ?-phenylpropoxy group at the 14-position. It is a highly potent analgesic drug several thousand times stronger than morphine, with a similar in vivo potency to etorphine. The 14-phenylpropoxy substitution appears to confer potent ?-opioid agonist activity, even when combined with substitutions such as N-cyclopropyl or N-allyl, which normally result in ?-opioid antagonist compounds. It has never been used in humans, but would be expected to produce effects similar to those of other potent opioid agonists, including strong analgesia, sedation, euphoria, constipation, itching and...
ISBN: 978-6-1326-1001-0
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Книга по требованию
Дата выхода: июль 2011