High Quality Content by WIKIPEDIA articles! Methoxetamine (MXE) or 3-MeO-2-Oxo-PCE is a chemical of the arylcyclohexylamine class which has been sold as a designer drug. It is a derivative of ketamine that also contains structural features of eticyclidine and 3-MeO-PCP. Methoxetamine is thought to behave as a NMDA receptor antagonist and dopamine reuptake inhibitor, though it has not been formally profiled pharmacologically. Methoxetamine differs from many other dissociative anesthetics of the arylcyclohexylamine class in that it was designed for grey-market distribution. Methoxetamine is a product of rational drug design: its N-ethyl group was chosen to increase potency, lessening the risk of interstitial cystitis that can result from...
High Quality Content by WIKIPEDIA articles! Methysergide (UML-491) is a prescription drug used for prophylaxis of migraine headaches and is sold under the brand names Sansert and Deseril in 2 mg dosages.
High Quality Content by WIKIPEDIA articles! Methyl isocyanate (MIC) is an organic compound with the molecular formula CH3NCO. Synonyms are isocyanatomethane, methyl carbylamine, and MIC. Methyl isocyanate is an intermediate chemical in the production of carbamate pesticides (such as carbaryl, carbofuran, methomyl, and aldicarb). It has also been used in the production of rubbers and adhesives. As a highly toxic and irritating material, it is hazardous to human health, and was involved in the Bhopal disaster which killed nearly 8,000 people initially and approximately 20,000 - 30,000 people in total.
High Quality Content by WIKIPEDIA articles! Methylglyoxal, also called pyruvaldehyde or 2-oxopropanal (CH3-CO-CH=O or C3H4O2) is the aldehyde form of pyruvic acid. It has two carbonyl groups, so it is a dicarbonyl compound. Methylglyoxal is both an aldehyde and a ketone.
High Quality Content by WIKIPEDIA articles! Methylcyclopentadienyl manganese tricarbonyl (MMT or MCMT) is an organomanganese compound with the formula (CH3C5H4)Mn(CO)3. Marketed as a supplement to the gasoline additive tetraethyllead to increase a fuel`s octane rating, MMT was later used in unleaded gasoline. Following the implementation of the Clean Air Act (United States) (CAA) in 1970, MMT continued to be used alongside TEL in the US during the phase-out of leaded gasoline (prior to TEL being finally banned from US gasoline in 1995) and was also used in unleaded gasoline until 1977. Ethyl Corporation obtained a waiver from EPA in 1995. The waiver allows the use of MMT in US unleaded gasoline (not including reformulated gasoline) at a...
High Quality Content by WIKIPEDIA articles! The Mildenhall Treasure is a major hoard of highly decorated Roman silver tableware from the fourth-century AD, found at West Row, near Mildenhall in the English county of Suffolk. It consists of two large serving platters, two small decorated serving plates, a deep fluted bowl, a set of four large decorated bowls, two small decorated bowls, two small pedestalled dishes, a deep flanged bowl with a deep, domed cover, five small round ladles with dolphin-shaped handles, and eight long-handled spoons (cochlearia). The hoard was discovered while ploughing in January 1942 by Gordon Butcher, who removed it from the ground with help from Sydney Ford, for whom he was working at the time. They did not...
High Quality Content by WIKIPEDIA articles! A miliarense (neuter form of the late Latin miliarensis "pertaining to a thousand") was the only fairly regularly minted silver coin issued by the late Roman and Byzantine Empires. It was struck with variable fineness, generally with a weight between 3.8 and 6.0 grams. The miliarense was struck from the beginning of the 4th century under Constantine I with a diameter of 23 mm. The name was also applied to Byzantine silver coins from the 7th to the 11th centuries (see Miliaresion).
High Quality Content by WIKIPEDIA articles! Milnacipran (Ixel, Savella, Dalcipran, Toledomin) is a serotonin–norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressive disorder in the USA, but it is in other countries.
High Quality Content by WIKIPEDIA articles! Mining in Cornwall and Devon began in the early Bronze Age approximately 2,150 BC and ended with the South Crofty tin mine in Cornwall closing in 1998. Tin and later also copper were the most productive of the metals extracted: some tin mining continued long after mining of other metals had become unprofitable.
High Quality Content by WIKIPEDIA articles! Mischmetal (from German: Mischmetall - "mixed metal") is an alloy of rare earth elements in various naturally occurring proportions. It is also called cerium mischmetal, rare earth mischmetal or misch metal. A typical composition includes approximately 50% cerium and 25% lanthanum, with small amounts of neodymium and praseodymium. Its most common use is in the "flint" ignition device of many lighters and torches, although an alloy of only rare-earth elements would be too soft to give good sparks. For this purpose, it is blended with iron oxide and magnesium oxide to form a harder material known as ferrocerium.
High Quality Content by WIKIPEDIA articles! The Missorium of Theodosius I is a large ceremonial silver dish preserved in the Real Academia de la Historia, in Madrid, Spain. It was probably made in Constantinople for the tenth anniversary (decennalia) in 388 of the reign of the Emperor Theodosius I, the last Emperor to rule both the Eastern and Western Empires. It is one of the best surviving examples of Late Antique Imperial imagery and one of finest examples of late Roman goldsmith work. It is the largest and most elaborate, and the most famous, of the 19 surviving vessels believed to represent largitio ("largesse") or a "ceremonial gift given by the emperor to a civil or military official".
High Quality Content by WIKIPEDIA articles! Moclobemide (sold as Aurorix, Manerix) is a monoamine oxidase inhibitor (MAOI) drug primarily used to treat depression and social anxiety. Although clinical trials with the medicine began in 1977, it is not approved for use in the United States. It is produced by affiliates of the Hoffmann–La Roche pharmaceutical company.
High Quality Content by WIKIPEDIA articles! Modafinil (Provigil, Alertec, Modavigil, Modalert, Modiodal, Modafinilo, Carim, Vigia) is an analeptic drug manufactured by Cephalon, and is approved by the U.S. Food and Drug Administration (FDA) for the treatment of narcolepsy, shift work sleep disorder, and excessive daytime sleepiness associated with obstructive sleep apnea. Because of the risk for development of skin or hypersensitivity reactions and neuropsychiatric disorders, the European Medicines Agency has recommended that new patient prescriptions should only be to treat sleepiness associated with narcolepsy. Because serious side effects will usually, if at all, appear within the first 12 weeks the guidance did not require patients...