High Quality Content by WIKIPEDIA articles! Rivastigmine (sold under the trade name Exelon) is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and dementia due to Parkinson`s disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting. The drug is eliminated through the urine, and appears to have relatively few drug-drug interactions.
High Quality Content by WIKIPEDIA articles! Ro01-6128 is a drug used in scientific research, which acts as a selective positive allosteric modulator for the metabotropic glutamate receptor subtype mGluR1. It was derived by modification of a lead compound found via high-throughput screening, and was further developed to give the improved compound Ro67-4853.
High Quality Content by WIKIPEDIA articles! Ro15-4513 is a weak partial inverse agonist of the benzodiazepine class of drugs, developed by Hoffmann–La Roche in 1984, and is structurally related to the benzodiazepine antidote flumazenil.
High Quality Content by WIKIPEDIA articles! Ro48-8684 is a water-soluble benzodiazepine derivative developed by Hoffman-LaRoche in the 1990s, which was designed along with Ro48-6791 as an improved replacement for midazolam, but ultimately proved to have little advantages over the parent drug and has not been introduced into clinical practice.
High Quality Content by WIKIPEDIA articles! Ro60-0175 is a drug developed by Hoffmann–La Roche, which has applications in scientific research. It acts as a potent and selective agonist for both the 5-HT2B and 5-HT2C serotonin receptor subtypes, with good selectivity over the closely related 5-HT2A subtype, and little or no affinity at other receptors.
High Quality Content by WIKIPEDIA articles! Robert M. Place (born 1947) is an artist and author known for his work on tarot history, symbolism, and divination.
High Quality Content by WIKIPEDIA articles! Robert II (2 March 1316 – 19 April 1390) became King of Scots in 1371 as the first monarch of the House of Stewart. He was the son of Walter Stewart, hereditary High Steward of Scotland and of Marjorie Bruce, daughter of Robert I and of his first wife Isabella of Mar. (The marriage of princess Marjorie took place in 1315, making Robert`s probable birth date early in 1316.)
High Quality Content by WIKIPEDIA articles! This table is designed to show the role(s) performed by each chemical element, in nature and in technology.
High Quality Content by WIKIPEDIA articles! Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. It is marketed by the pharmaceutical company GlaxoSmithKline (GSK) as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Annual sales peaked at approximately $2.5bn in 2006, but declined after reports of adverse effects. The drug`s patent expires in 2012.
High Quality Content by WIKIPEDIA articles! Rosuvastatin (marketed by AstraZeneca as Crestor marketed by Abbott Healthcare Pvt. Ltd. in India as `R2`) is a member of the drug class of statins, used to treat high cholesterol and related conditions, and to prevent cardiovascular disease. It was developed by Shionogi.
High Quality Content by WIKIPEDIA articles! Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson`s disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours.
High Quality Content by WIKIPEDIA articles! Roussin’s Red Salt is the inorganic compound with the formula K2. This metal nitrosyl was first described in 1858, making it the first synthetic iron-sulfur cluster.
High Quality Content by WIKIPEDIA articles! Rufinamide is an anticonvulsant medication. It is used in combination with other medication and therapy to treat Lennox–Gastaut syndrome and various other seizure disorders. Rufinamide, a triazole derivative, was developed in 2004 by Novartis Pharma, AG, and is manufactured by Eisai.
High Quality Content by WIKIPEDIA articles! A Rydberg atom is an excited atom with one or more electrons that have a very high principal quantum number. These atoms have a number of peculiar properties including an exaggerated response to electric and magnetic fields, long decay periods and electron wavefunctions that approximate, under some conditions, classical orbits of electrons about the nuclei. The core electrons shield the outer electron from the electric field of the nucleus such that, from a distance, the electric potential looks identical to that experienced by the electron in a hydrogen atom.
High Quality Content by WIKIPEDIA articles! The s-block of the periodic table of elements consists of the first two groups: the alkali metals and alkaline earth metals, plus hydrogen and helium.
High Quality Content by WIKIPEDIA articles! The S-process or slow-neutron-capture-process is a nucleosynthesis process that occurs at relatively low neutron density and intermediate temperature conditions in stars. Under these conditions the rate of neutron capture by atomic nuclei is slow relative to the rate of radioactive beta-minus decay. In the S-process, a stable isotope captures a neutron, but the radioactive isotope that results decays to its stable daughter before the next neutron is captured. This process produces stable isotopes by moving along the valley of beta-decay stable isobars in the chart of isotopes. The S-process produces approximately half of the isotopes of the elements heavier than iron, and therefore plays an...
High Quality Content by WIKIPEDIA articles! Sabcomeline (Memric; SB-202,026) is a selective M1 receptor partial agonist that was under development for the treatment of Alzheimer`s disease. It made it to phase III clinical trials before being discontinued due to poor results.